Nikki Lee (nee Chow) was born and raised in Hong Kong and attended Sevenoaks School Sixth Form.

She spent one year at the University of Bristol before transferring to the University of Pennsylvania and graduated with a Bachelor of Arts with Honours in Communication.

She returned to the UK in 2005 to study medicine at Barts and the London School of Medicine and Dentistry, graduating with Distinction in Clinical Sciences in 2010. She did her Foundation Year training in West London and then commenced Obstetrics and Gynaecology speciality training in South London. She married Henry Lee in 2010 and they spent a few years in Hong Kong during which they had two children. She lives with her husband and two children in London and is works at Guys' and St Thomas' NHS Foundation Trust.